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Cefquinome sulfate sterile micronized 118443-89-3

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US $1,200 - 2,500 / Kilogram | 1 Kilogram/Kilograms (Min. Order)
Supply Ability:
1000 Kilogram/Kilograms per Month
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ANY
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Overview
Specifications
CAS No.:
118443-89-3
MF:
C23H24N6O5S2.H2SO4
Place of Origin:
Shandong, China (Mainland)
Type:
Antibiotic and Antimicrobial Agents
Grade Standard:
Medicine Grade
Usage:
Animal Pharmaceuticals
Brand Name:
lukang
Model Number:
sterile raw material
Purity:
not less than 98%
Appearance:
White or almost white powder
PH:
1.6~2.6
Water Content:
2.5~4.0%
Specific optical rotation:
+16.5°~+22.5°
Total impurities:
NMT 2.0%
Assay:
80.0~85.0%
Packaging & Delivery
Packaging Details:
aluminum tins, 5kg/tin,2tins/carton
Delivery Detail:
ONE WEEK AFTER PAYMENT

Specifications

it is used in respiratory infection caused by sensitive bacteria, acute Mastitis, Septicemia, hysteritis- mastit

Product name:Cefquinome Sulfate

Chemical name:(6R,7R)-7-(Z)-2-(2-amino-4- thiazolyl)-2- methoxy imino acetylamino-3-5,6,7,8- tetrahydroquinoline Methyl-8- oxo -5- thia -1- Diazabicyclo4.2.0octyl -2-ene-2- carboxyl sulfate

Molecular formula:C23H24N6O5S2·H2SO4

Molecular weight:626.69

Description:off white or light yellow crystal powder. freely soluble in water, slightly soluble in ethanol and hard dissolve in ether and chloroform

Quality Specification Content: count with anhydride , CefquinomeC23H24N6O5S2≥80.0%      moisture content :≤4%, ignited residue ≤0.5%, heavy metals: ≤20ppm

Pharmacological action Cefquinome has broad- spectrum antibacterial activity and has higher activity to Staphylococcus aureus, Streptococcus, Pseudomonas aeruginosa, SEnterobacteriaceae (Salmonella, Enteric bacilli .etc.). It also has good activity to Staphylococci and Enterococcus which has drug resistance to meticillin sodium. Cefquinome can be well absorbed by intramuscular injection and hypodermic injection than by oral administration, the peak time is short , the bioavailability is high.

indicationThe product is mainly used in respiratory infection caused by sensitive bacteria, acute Mastitis, Septicemia, hysteritis- mastitis-agalactia syndrome of swine.

Usage and DosageIntramuscular injection. cattle: 1mg/kg.b.w, swine: 2mg/kg.b.w, during 3-5 days, once a day.

Precaution:the product is prohibited to use for the creature which are hypersensitiveness to β-lactam antibiotics

withdrawal period5 days.

Package1kg/drum, 5kg/drum, 10kg/drum.

Preparation Injection.

Storage Stored in a cold place and protected from light with a container tightly closed.

Expiry2 years.

 

 

Shandong Lukang Record Pharmaceutical Co., Ltd.

Test items

Enterprise specification

Test results

Appearance

White to light yellow powder

Off-white powder

Identification

HPLC

The retention time of the principal peak in the chromatogram obtained with the test solution corresponds to that of the principal peak in the chromatogram obtained with reference solution.

Conform

Reaction of sulphates

White precipitate is formed

Conform

Appearance of solution

Clarity

Its opalescence is not more pronounced than that of reference suspension I.

Conform

Color

No more intensely coloured than reference solution Y10 or GY10

Less intensely coloured than reference solution Y7

PH (0.1g/ml)

1.6~2.6

1.7

Water Content

2.5~4.0%

3.0%

Specific optical rotation

+16.5°~+22.5°

+19.5°

Heavy metal

NMT 0.0020%

NMT 0.0020%

Residue of ignition

Not more than 0.3%

0.21%

Related substances

Cefotaxime

NMT 0.50%

0.011%

5,6,7,8-Tetrahydroquinoline

NMT 0.50%

0.06%

Any other

individual impurity

NMT 0.20%

0.17%

Total impurities

NMT 2.0%

0.748%

Residue solvents

Dichloromethane

NMT 0.0600%

Not detected

Toluene

NMT 0.0890%

0.0000252%

Ethanol

NMT 0.5000%

0.001252%

Acetone

NMT 0.5000%

0.02027%

Benzene

NMT 0.0002%

0.00001%

Assay(Cefquinome)

80.0~85.0%

83.2%

Bacterial endotoxin

Less than

0.10EU/mg(Cefquinome)

Conform

Sterility

No growth of micro-organisms should occur after 14 days of incubation

Conform

Particle size

d10:NMT 1.0μm

0.94μm

d50:NMT 4.0μm

2.4μm

d90:NMT 7.0μm

5.6μm

Storage Condition: Protected from light and keep in an airtight container at 2~10°C

 

 

 

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China (Mainland) | Manufacturer, Trading Company
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