The Single Pot Technology has changed the conventional method of Granulation into more safe, Contained and quality process with increased yields. Thus Fluid Bed Coater can replace RMG, FBD, Multi-Mill and Blender.
All in one piece of equipment:
- Dry Mixing,
- Wet Granulation,
Granulation/Drying,Pellet (Controlled-Release Coating): Film Coating, Enteric Coating and Powder Coating
Principle of operation:
With fluid bed coating, particles are fluidized and the coating fluid sprayed on and dried. Small droplets and a low viscosity of the spray medium ensure an even product coating.
1. Top Spray:
(1) Pharmaceutical: For medicines, biopharmaceutical, and Chinese medicine’s granulation or drying
(2) Food: Instant food, juice powder, seasoning, food additive, lactic acid bacteria’s granulation or drying
2. Bottom Spray: Medicines and healthy food for a controlled release of active ingredients
Drying: Wet powder or granules drying
Top Spray: Spray binder on powder for granulation
Bottom Spray: Pellet Suspension Coating or Film Coating, Enteric Coating
Top Spray Granulation:
Spray atomized binder or active ingredients on the fluidized to form the uniformity granules.
Bottom Spray Coating:
The concept of Bottom Spray Coating is also known as Air Suspension Coating, is to separate pellets or granules from one another in an air stream and spray a coating binder onto the pellets or granules while they are suspended. When the hot air passes through the bottom screen of a container and draft tube (Wuster insert), it will generate the siphon principle. The granules will fall down and will be sucked into the draft tube (Wuster insert) again, while the bottom spray gun will spray towards top to achieve coating purpose.
- Follow the regulations of cGMP, GMP, FDA
- Multi-purposes: One machine can perform multiple functions, Drying, Granulation, Powder Coating, Pellet Film Coating, Pellet Enteric Coating
- High drying efficiency: Fluid Bed Coater is 10 ~ 20 times faster than conventional drying oven
- Temperature control can be controlled from room temperature to 100 Degree Centi., law temperature drying at 35-40 Degree Centi. and an optional dehumidifier can be installed for thermo-sensitive product like probiotic
- The inlet air is filtered by a final-filter to secure the cleanness of the inlet air
- Touch Screen Interface control system: All the parameters can be memorable, multilevel of passwords can be set, connect to the diagrams printing are optional available
- Two sets of valves are interacting automatically to suspend the granules continuously
In pharmaceutical development tablets can be coated for several reasons such as:-
- To modify and control the release of active ingredient (controlled or modified release)
- To enable the mixed presentation of otherwise incompatible formulations
- To mask taste or odor
- To improve appearance
- To facilitate identification
- To facilitate swallowing
- To protect the core from light or moisture to improve stability
Benefits of Fluid Bed Coater
- Only ONE product container for all unit operations
- Fluid Bed Granulator - Fluid Bed Dryer - Fluid Bed Coater, ALL in 1 container,Only one design/height for all unit operations.Reduced building envelope in both height and footprint
- Linear scale up.Ready for fully contained loading and unloading.Superior product homogeneity.
- The design of cylinder for accelerator or cone for decelerate can Coating of granule, big granule and pellets.
We are happy to carry out trials with your materials in our laboratory or for longer periods of evaluation rental machines are available for on-site trials.
Our promise: To meet our customers high demands on quality, economic efficiency, production safety and environmental protection.
Please do contact us for any Pharmaceutical Machine required by your esteem organization. i.e. R&D Tablet Press, Single Rotary Tablet Compression Machine, Double Rotary Tablet Compression Machine, Veterinary (Bolus) Tablet Making Machine, Seiving Machine Vibro Sifter,Dies and Punches for Tablet Press, Mini Rapid Mixer Granulator, Roll Compactor Cantilever,Rapid Mixer Granulator, Fluid Bed Processors, Mini Roll Compactor, Communiting Mill, Fluid Bed Dryer, Auto Coater, Colloid Mill, Multi Mill