Feverfew helps maintain normal blood vessel tone. Parthenolide also helps normalize the functions of platelets in the blood system by inhibiting platelet aggregation,reducing serotonin release from platelets and blocking the formation of pro-inflammatory mediators.
Feverfew is a member of the daisy family. It has been used in traditional medicine as far back as the 1st century for inflammatory conditions and to prevent the occurrence of migraine headaches. Traditionally consumed as whole of dried leaves, or as a tea, feverfew is available in supplemental form as an encapsulated powder standardized for the potential active ingredient known as parthenolide.
Laboratory and clinical studies have shown an effect of feverfew leaves and extracts on inflammatory processes including arachidonate metabolism and platelet functions. Feverfew extracts produce a clear inhibition of histamine release and production of prostaglandins, which may explain some of the anti-inflammatory activities of feverfew. Parthenolide and related sesquiterpenes may interfere with serotonin release from platelets (excess serotonin release from platelets has been suggested as a primary cause of migraines), suggesting a possible mechanism by which feverfew functions to inhibit smooth muscle cell contraction and prevent migraines from occurring.
1. Preventing migraine headaches 2. Easing menstrual cramps 3. Relieving the pain and inflammation of arthritis
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