Epimedium herb is an old chinese herb used since ancient days thousand years ago,This herb got used wildly and effectively in below field:
Libido Stimulating,ED treatment and related similar symptoms treatment,such like Chronic Renal Insufficiency and end-state renal failure(ESRF),sexual disorder in chronic renal failure cases:
Mechanism of Epimedium herb and its useful fractions and isolated components on the effects related with phallus got attentioned from a lot of modern scientific studies,the compositive mechanism could be briefly identified and understood as:
(1).Works on multitargets in nitric oxide (NO)/cyclic guanosine monophosphate(cGMP)/phosphodiesterase 5(PDE 5) pathway;
(2).PDE5 mRNA expression inhibition especially PDE5A1 inhibition,works to inhibitory to all three PDE5 isoforms(PDE5A1, A2, and A3) ,also inhibite PDE-6(phosphodiesterase-6);
(4).Regulates the activity of NO-cGMP signal pathway on CC to enhance erectile function;
(5).increases the erectile function (ICP) and restores the eNOS(expression of the nitrogen oxide synthase) expression,PSM(percent of smooth muscle) increase in the CC(corpus cavernosum);
(6).Estradiol Production of Granulosa cells promption,Corticosterone Production stimulation,Release Erectogenic and Neurotrophic effects,Testosterone mimetic properties;
Components specific of ED treatment got attentioned included: Epimedium brevicornum Maxim Water Extract(EbM) and Hydrophobic compounds,isolated components icariin,icaritin(3,7-bis(2-hydroxyethyl)),inhibitors with molecular weights over 500 still effective.
Some combinative investigation of TCM recipe EXD(Er Xian Decoction) and another recipe named Etana got compared yet.The component icariin combined with resveratrol and LBP got found release strong property of Spermatogenic disturbance anti-radiation.
Application and Property
Chronic Renal Insufficiency
Components specific of related got attentioned
Species specific difference got attention
Negative Non-Estrogenic property got attentioned
Effects on the immune system
Specific fractions and components of related attentioned
Coronary Heart Disease Prevention
Antioxidative Effect and Atherosclerosis Prevention
Other identified application and property included:Diabetic Property,Angiogenetic Activity,Antihepatotoxic Activity,Obesity Treatment,Melanogenesis Inhibitor,Hypopigmentation,Splenocyte Proliferation Inhibition,Antibacteria Property,etc.
Anything we can do for you, feel free to contact us.Your request is our driving force and aggressive, your satisfaction is always our goal.
Click our video show to know more of us,your calling and visiting will be warmly welcomed!
Hunan Goldliloo Pharmaceutical Co., Ltd is located in 29-30 floors of TJFJ building, Changsha city, Hunan province, which is a modernized pharmaceutical enterprise specializing with I S O 9 0 0 1 in manufacturing and exporting rutin / troxerutin, Stevia, Lingonberry Powder, elderberry powder/ anthocyanin, black currant extract (anthocyanin), raspberry powder, black currant powder/ anthocyanin, sweetberry powder, Rose hip flavone/VC/Sponin , blueberry powder/ anthocyanin, Epimedium Extract, ant ... View detail