Chondroitin sulfate sodium is the sodium salt of the sulfated linear glycosaminoglycan obtained from bovine, porcine, or avian cartilages of healthy and domestic animals used for food by humans.
II :Chondroitin Sulfate Function:
Chondroitin's functions depend largely on the properties of the overall proteoglycan of which it is a part. These functions can be broadly divided into structural and regulatory roles. However, this division is not absolute, and some proteoglycans have both structural and regulatory roles (see versican).
Chondroitin sulfate is a major component of extracellular matrix, and is important in maintaining the structural integrity of the tissue. This function is typical of the large aggregating proteoglycans: aggrecan, versican, brevican, and neurocan, collectively termed the lecticans.
1.As a health food or health care drugs, Chondroitin Sulfate is used to cure coronary heart disease, angina, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases in the long-term, no obvious side effects, can significantly reduce the incidence of coronary heart disease and mortality. Clinical application of long-term found that the walls of arteries and veins of fat, such as lipid deposition can be effectively removed or reduced to a significant reduction in plasma cholesterol, thus preventing atherosclerosis formation.
2.Chondroitin Sulfate for the treatment of neuralgia, nerve migraine, joint pain, arthritis and scapular joint pain, and abdominal pain after the operation.
(2) a solution containing 0.5 g in 10 ml of water meets the requirements of the test for sodium <191>.
Clarity and color of solution
Its absorbance is not greater than 0.35.
Specific rotation <781S>
-20 ° -30.0°
Microbial enumeration <2021>
The total bacterial count does not exceed 1000 cfu / g, and the total combined molds and yeasts count does not exceed 100 cfu / g. It meets the requirements of the tests for absence of Salmonella species, and Escherichia coli.
5.5 ~ 7.5 in a solution (1 in 100)
Loss on drying <731>
Not more than 10.0%
Residue on ignition <281>
20.0% ~ 30.0%
Not more than 0.50%
Not more than 0.24%
Heavy metals, Method II <231>
Not more than 0.002%.
Organic volatile impurities, Method I
Ethanol: not more than 0.5%
Electrophoretic purity <726>
Any individual impurity: not more than 2%.
Limit of protein
Not more than 6.0%
Content of chondroitin sulfate sodium
Brief Introduction of Shandong Zhongyuan Greentech Co.,ltd:
Founded in 1997, Shandong Zhongyuan is now an experienced pharmaceutical intermediates manufacturer specializing in chondroitin sulfate industry for over ten years. Its products scope covers sodium and calcium chondroitin sulfate bovine, porcine,chicken,fish.