Recombinant Human Coxsackie Virus And Adenovirus Receptor, His-Fc

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Store at 4C short term (1-2 weeks). Aliquot and store at -20C or -80C. Avoid repeated freeze / thaw cycles.

CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a 46 kDa type I transmembrane glycoprotein expressed on the basolateral surface, and belongs to the CTX family of the Ig superfamily. It is a receptor for group B coxsackieviruses and subgroup C adenoviruses and also acts as a homophilic adhesion molecule within junctional complexes, notably between epithelial cells lining body cavities and within myocardial intercalated discs. CXADR structrually comprises two extracellular immunoglobulin domains, a transmembrane helix and a C-terminal intracellular domain. The N-terminal Ig domain (D1) of CXADR is necessary and sufficient for adenovirus binding. The C-terminus interacts with several cytoplasmic junctional proteins, microtubules and the actin cytoskeleton. Pairs of transmembrane domains of CXADR associate with each other in a detergent cloud that mimics a cellular plasma membrane. Variants of CXADR are attached to the cell membrane by a GPI- anchor.

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Creative Biomart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

We are offering more than 1,000 recombinant proteins, peptides and antibodies. All the products are rigorously tested to meet the most demanding research needs. At the same time, lowest prices in the industry are always guaranteed.... View detail

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Main Products: peptides,chemicals,recombinant protein,antibodies,elisa kits  

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Experience: Established 2005

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