Tetrodotoxin(TTX), CAS: 4368-28-9

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US $100-200 / Milligram | 10 Milligram/Milligrams (Min. Order)
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1 Kilogram/Kilograms per Month
Overview
Quick Details
CAS:
4368-28-9
Packaging & Delivery
Packaging Details
vials
Delivery Time
3Days

As a professional manufacturer & exporter, we supply tetrodotoxin which features are as below:

 

Appearance: White powder indefinite crystal

 

Purity (HPLC): TTX 99.9% , not less than 99%

 

Preparation Note

Tetrodotoxin is soluble in dilute citrate or acetate buffer at 1 mg/ml (pH 4-5). Aqueous solutions are stable at pH 4-5 if stored frozen. However, tetrodotoxin is unstable in strong acid or alkaline solutions and is destroyed by boiling at pH2.

Application

Tetrodotoxin has been used as standard during HPLC-based analysis of biotoxins fromP. punctata tentacles whole crude extract (PHY-N)1. Tetrodotoxin has also been used to study its effects on low-threshold transient (LTT) Ca2+ currents in rat hippocampal interneurons2.

Biochem/physiol Actions

Reversible, selective blocker of Na+ channels; blocks propagation of impulses in excitable membranes. Used to characterize sodium channels in excitable membranes and to study the role of sodium channels in normal physiology and disease.

assay  ≥99% (HPLC)
form  powder
color  white
solubility  dilute citrate or acetate buffer: soluble1 mg/mL (dissolve at pH 4-5. Aqueous solutions, pH 4-5, are stable if stored frozen.)
 strong acid or alkaline solutions: unstable (destroyed by boiling at pH 2.)
storage temp.  2-8°C