Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, relieve the discomfort of mouth sores and in nasal spray form, to treat allergic rhinitis. It is a more potent derivative of triamcinolone, and is about 8 times as potent as prednisone.It is also known under the brand names Kenalog and Volon A as an injection to treat allergies, arthritis, eye diseases, intestinal problems and skin diseases. Cholecalciferol (also known as toxiferol) is a form of vitamin D, also called vitamin D3.It is structurally similar to steroids such as testosterone, cholesterol, and cortisol (though vitamin D3 itself is a secosteroid).
Triamcinolone acetonide should not be used by those with tuberculosis or untreated fungal, bacterial, systemic viral or herpes simplex infections without consulting a doctor first. Few serious adverse effects were noted in clinical trials, with pharyngitis, rhinitis, headache and epistaxis being the more common ones.Overdosage is improbable, and the effects of such an overdose appear to be confined to gastrointestinal upset. Individuals with geographic tongue (benign migratory glossitis) can apply it at bedtime to the affected area which heals overnight.It has been used in various eye diseases and has been found useful in reducing macular Edema. Drug trials have found it to be as efficient as anti-VEGF drugs in eyes with artificial lens over a 2-year period. Complications of its use in eye are - cataract and glaucoma.When applied as a topical ointment @ USP,0.1% it is used for blistering from poison ivy, oak, and sumac. Applied to skin avoiding eyes, mouth, and genital area. Provides immediate relief and is used before going to oral prednisone.Intramuscular injection of triamcinolone acetonide may be indicated for the control of severe or incapacitating allergic states for which conventional treatments have failed, such as asthma, atopic dermatitis, contact dermatitis, perennial or seasonal allergic rhinitis, serum sickness, and transfusion and drug hypersensitivity reactions.
7-Dehydrocholesterol is the precursor of vitamin D3. Within the epidermal layer of skin, 7-Dehydrocholesterol undergoes an electrocyclic reaction as a result of UVB radiation, resulting in the opening of the vitamin precursor B-ring through a conrotatory pathway. Following this, the previtamin D3 undergoes a [1,7] antarafacial sigmatropic rearrangement and therein finally isomerizes to form vitamin D3.Cholecalciferol is then hydroxylated in the liver to become calcifediol (25-hydroxyvitamin D3).Next, calcifediol is again hydroxylated, this time in the kidney, and becomes calcitriol (1,25-dihydroxyvitamin D3). Calcitriol is the most active hormone form of vitamin D3
Our company - Xian Wango Biopharm Co., Ltd. is a professional manufacturer of pharmaceutical intermediates, it is belongs to the Asia Forsesight-care Group . And we also produce plant oils & herb extract. You can buy goods from factory directly, saving cost for you! We supply services to customers in 130 countries every year.
With rich experience, we can deliver our goods to you smoothly. With 24-hour services, your inquiry could be replied within 6 hours. With thousands of stoc...