Vinpocetine (Ph.F), CAS NO. 42971-09-5

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Quick Details

CAS No.:
42971-09-5
Place of Origin:
Hunan China (Mainland)
Type:
Blood System Agents,Cardiovascular Agents,Central Nervous System Agents
Grade Standard:
Medicine Grade
Brand Name:
Inner Natural
Model Number:
EP
Purity:
99%
Product name:
Vinpocetine
Formula:
C22H26N2O2
Molecular Weight:
350.46 g/mol
CAS N.:
42971-09-5

Specifications

Complies with EP
99% Vinpocetine by HPLC
Vasodilatory action, Improves brain blood flow

Applications

 

 

     Vasodilatory action measured by an inhibition of the phosphodiesterase activity and increase in the levels of AmpC, with an increase of the blood flow by diminishing the vascular resistance.

 

     Antiplatelet action.

 

     Improvement of the hemorheological conditions in the microcirculation upon increasing the deformability of the erythrocytes.

 

     Brain cells' increased tolerance to hypoxia (lack of oxygen in the brain) and/or ischemia (permanent or transitory decrease of blood flow).

 

     Increase in the levels of oxygen and use of glucose in the neurons.

 

     Improvement in terms of production of neurotransmitters such as dopamine and noradrenaline, to which its nootropic effect has been attributed.

 

 

Source

 

Vinpocetine is a semisynthetic alkaloid of Vincamine (ethyl ester of Apovincamine).

 

 

 

Vincamine production process is based on synthesis from tabersonine of the Voacanga africana.

 

 

 

Voacanga Africana

 

 

Voacanga Africana, a West African tree can give you mild trip and let you have hallucinogenic experience. It is very popular among the people who seek experimental experiences. The tree is quite easy to grow, within the confines of your garden. With a height up to 30 feet, and leaves up to 30 cm long, the tree bears yellowish flowers when fully matures, ultimately turning into berries with yellow seeds. Its roots, barks and seeds contain a little amount of Ibogaine.

 

 

 

Traditional medicinal uses

 

Voacanga has a broad range traditional medicinal uses. In Cote d’ Ivore this plant is used against leprosy, diarrhea, generalized edema, convulsions in children, madness, as a diuretic, and infant tonic. A decoction of the stem bark and root is used in the treatment of mental disorders and the latex is applied to carious teeth. The decoction of the bark is considered an analgesic and is added to embrocating mixtures used as pastes during fracture repair. Bark and root decoctions are also used to treat cardiac spasms. The fruit decoction is used as a disinfectant, and the leaf decoctions to treat asthma to children. In southeastern Nigeria the plant is featured in many healing rituals, including some to in­duce hallucinations and trances in religious rituals. In Congolese traditional medicine preparations of extracts containing V. africana are used as anti-amoebial. Intestinal amoebiasis is one of the current diseases in tropical regions causing diarrhea. It has been reported that V. africana has active activity against Entamoeba histolytica in vitro

 

Specifications

 

 

Name of the plantVoacanga africana
Part of the plant usedSeeds
FormulaC22H26N2O2
IUPAC NameEburnamenine-14-carboxylic acid ethylester
SynonymsEthyl-apovincaminate; (3 , 16 ) - Eburnamenine-14-carboxylic acid ethyl ester.
Molecular Weight350.46 g/mol
CAS N.42971-09-5
Structural Formula 
AppearanceWhite to slightly yellow crystals, or crystalline powder, odourless
SolubilityPractically insoluble in water, soluble in methylene chloride, slightly
soluble in anhydrous ethanol
Melting pointBetween 150° and 153°C
IdentificationIR
Specific optical rotationBetween + 127 and + 134
Absorbance E1%1cm (254 nm)Between 330 and 343
Loss on dryingNMT 0.20 %
Sulphated ashNMT 0.10 %
Heavy MetalsNMT 10 ppm
SulphatesNMT 0.03 %
Assay Between 99.0 % and 101.0 %
MicrobiologyComplies with EP
StorageSealed container and protected from light

 

 

 

 

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Changsha Inner Natural Inc. (named INI for short) has been dedicated to the research and development of innovative nutraceutical ingredients since 2000. INI is a Developer, Manufacturer, Exporter and Primary Supplier of the most remarkable alternative and complementary herbal health products and raw materials today. INI develops and manufactures superior nutraceutical ingredients.

INI has advanced in-home lab as well as professional R&D people to swift response to any of your requests. We ... View detail

Basic Information

Product/Service (We Sell): Plant Extract  
Number of Employees: 51 - 100 People  

Trade & Market

Main Markets: North America
Eastern Europe
Southeast Asia
Oceania
Western Europe
Northern Europe
Total Annual Sales Volume: US$1 Million - US$2.5 Million  
Export Percentage: 71% - 80%  

Factory Information

Contract Manufacturing: OEM Service Offered   Design Service Offered   Buyer Label Offered  

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Experience: Established 2005

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