aloe-emodin

FOB Reference Price:Get Latest Price
US $1-500 / Kilogram | 1 Gram/Grams (Min. Order)
Supply Ability:
1200 Kilogram/Kilograms per Day
Port:
XA
Overview
Specifications
Type:
Herbal Extract
Variety:
Aloe Vera Extract
Form:
Powder
Part:
Leaf
Extraction Type:
Solvent Extraction
Packaging:
Drum
Place of Origin:
Shaanxi, China (Mainland)
Grade:
top
Brand Name:
sp
Model Number:
WER54
color:
yellow
Packaging & Delivery
Packaging Details:
carton drum
Delivery Detail:
2 working day

Specifications

Chemical Name :Aloe-emodin
CAS Number :481-72-1
Molecular Formula :C15H10O5
Molecular Weight :270.24

aloe-emodin (AE), a hydroxyanthraquinone present in Aloe vera leaves, has a specific in vitro and in vivo antineuroectodermal tumor activity. The growth of human neuroectodermal tumors is inhibited in mice with severe combined immunodeficiency without any appreciable toxic effects on the animals. The compound does not inhibit the proliferation of normal fibroblasts nor that of hemopoietic progenitor cells. The cytotoxicity mechanism consists of the induction of apoptosis, whereas the selectivity against neuroectodermal tumor cells is founded on a specific energy-dependent pathway of drug incorporation. Taking into account its unique cytotoxicity profile and mode of action, AE might represent a conceptually new lead antitumor drug.

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