cas : 314728-85-3 Sunifiram 99% white fine powder -- the best Nootropic

FOB Price: US $1.98 - 15 / Gram Get Latest Price
Min.Order Quantity: 1 Gram/Grams
Supply Ability: 100 Kilogram/Kilograms per Week The small sample is available
Port: TianJing Port
Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram,paypal
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Quick Details

CAS No.:
314728-85-3
Other Names:
1-benzoyl-4-propanoylpiperazine
MF:
C14H18N2O2
Place of Origin:
Shaanxi China (Mainland)
Type:
Cardiovascular Agents
Grade Standard:
Medicine Grade,Tech Grade
Brand Name:
www.foresight-care.com
Model Number:
IQ005
Purity:
99%
Manufacturer:
Xi'an Wango biopharm
Appearance:
white crystal powder
Assay Test Method:
HPLC
Standard:
USP/BP/CP
Application Area:
Pharmaceutical raw intermediates
Stability:
stable
Loss On Drying:
2.5%
Shelf life:
2 years
Storage:
Dry place in sealed container

Packaging & Delivery

Packaging Detail: 1. 1g 50g 500g 1kg in a Al foil bag & 25kg/barrel. 2. The packaging can be customised.
Delivery Detail: 2-3days for Sample Order ; 5-15 days for Large Orders.

Specifications

1. Hot product of from manufacturer
2. Specification: 99%
3 Product name: Sunifiram
4 Other Code: DM235

Product details:

 

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric 

modulator of AMPA receptors, and has nootropic effects in animal studies with significantly

 higher potency thanpiracetam. A number of related compounds are known, the best known 

being unifiram (DM-232)

Product Name

Sunifiram (DM-235)

Synonym

1-benzoyl-4-propanoylpiperazine

Molecular Formul

C14H18N2O2

Molecular Weight

246.304

CAS No.

314728-85-3

Purity 99.8%

Melting point 94.5°C-95.5°C

Appearance Off-white to white crystalline powder 

Introduction

This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.

Benefits

1.Sunifiram activates AMPA-mediated neurotransmission. 

2.Enhancing LTP in a bell-shaped dose–response relationship.  

3.Sunifiram aids in the release of acetylcholine in the cerebral cortex.

 

Product Description

Sunifiram is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the racetam family of nootropics (yet by being derived from them, it is still commonly associated with this class).

Sunifiram has mechanisms similar to Nefiracetam in the hippocampus, and sunifiram shows anti-amnesiac properties and is a cognitive enhancer. Its anti-amnesiac activity is several orders of magnitude greater (significantly more potent) than piracetam, and preliminary evidence suggests it has a very good safety profile.

This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

 

Packaging & Delivery

 

1•  Packaging Detail: 100/bag,500g/bag,1kg/bag,25kg/drum

     Delivery Detail:  According the quantity(Small order:3-5days; Big order:5-15days)

 

2•  Payment terms: T/T 100% in advance by Western union & Company bank account and Paypal(small sample only)

 

3•  Payment way: We accept payments throught Telex transfer, Paypal, Western Union...

 

4•  Shipping methods: We offer several delivery services to suit all customer needs. By Courier or Air and Sea, such as: DHL, FEDEX, TNT, UPS, EMS.

 

Website: www.foresight-care.com

 

  

 

 

 

 

 

 

 

 

 

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Our company - Xian Wango Biopharm Co., Ltd. is a professional manufacturer of pharmaceutical intermediates, it is belongs to the Asia Forsesight-care Group . And we also produce plant oils & herb extract. You can buy goods from factory directly, saving cost for you! We supply services to customers in 130 countries every year.

With rich experience, we can deliver our goods to you smoothly. With 24-hour services, your inquiry could be replied within 6 hours. With thousands of stock items, ... View detail

Basic Information

Product/Service (We Sell): supplier,Intermediates,Peppermint oil,Coluracetam,kava extract  
Number of Employees: 101 - 200 People  

Trade & Market

Main Markets: South America
North America
Western Europe
Eastern Europe
Total Annual Sales Volume: US$50 Million - US$100 Million  
Export Percentage: 91% - 100%  

Factory Information

Number of R&D Staff: 5 - 10 People  
Number of QC Staff: 11 - 20 People  

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Verified Supplier - Xian Wango Biopharm Co., Ltd.
China (Mainland) | Trading Company | Contact Details
Experience: Established 2013

Communicate with Supplier:

Ms. Karen Li
Ms. Karen Li:
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