MD-12 Advanced Anti-Age Cream

Part of Mediderm Rx- Anti-Age Rx line.

Brings together everything mediderm laboratories research has learned about anti-aging skincare, precious, luxury ingredients from all over the world are combined in a specific order. The result is the most remarkable cream we have created, bringing instant gratification plus long-term results. So your skin look younger, radiant and lifted. Today, tomorrow and years from now. This unique formula helps boost skin own production of the protein that helps keep skin from sagging. Innovative ingredients help prevent collagen from losing its spring and encourage skin to boost its natural production of collagen. So skin recovers its spring and bounce, and looks toned, lifted. The light weight cream restores and strengthens the lipid barrier, so skin can protect itself naturally. Md-12 contains more than 12 powerful ingredients: Kinetin, Matrixyl 3000, alpha lipioc acid, dmae, vitamin e, vitamin c, vitamin a, copper, q-10, marine collagen, hydrolyzed wheat protein, hyaluronic acid what is matrixyl 3000 the results generated by the clinical studies show excellent anti-wrinkle efficacy for matrixyl 3000 after 2 months of daily application: Reduction in the volume (-18% ) and depth of deep wrinkles (-15% ) giving rise to smoother skin (-14% roughness) and a lifted surface (-16% complexity) which, in the cutometric study, was reflected in a improvement in tone (15% ) . The percentage decrease in the number and amplitude of the wrinkles on the analyzed surface was very strong (-44% ) . This effect was also correlated with the visible difference between t0 and t56 the two peptides, pal-ghk and pal-gqpr, combined in the product matrixyl 3000, showed a complementary gene activation profile with stimulation of protein remodeling (urokinase, timp1, iysyl oxidase, tenascin, syndecan) , and cell proliferation, migration and installation (egf, pdgf, rho, catenin, laminin, fibronectin) . Moreover, epidermal function progressed toward microvascularization and innervation (vegf and ephrin) . In vitro, the two peptides showed synergistic effects on the synthesis of collagen 1, fibronectin and hyaluronic acid. A clinical trial conducted in 2 groups of 24 subjects enabled comparison of the benefits obtained with matrixyl 3000 vs. Matrixyl and matrixyl 3000 vs. Placebo, thus validating the synergistic approach adopted by combining the two peptides. After 2 months of daily application of matrixyl 3000 (3% formula, the following points were observed: -reduction in the mean depth of the main wrinkle (-15% ) and in its volume (-18% ) -reduction in roughness (-14% ) and complexity (-16% ) , a surface lifting parameter-decrease in the area occupied by deep wrinkles (> 200 nm) (-44% ) , giving rise to a decrease in density (15% ) .