Glutaraldehydeis an organic compoundwith the formula CH2(CH2CHO)2. A pungent colorless oily liquid, glutaraldehyde is used to sterilise medical and dental equipment. It is also used for industrial water treatmentand as a preservative. It is mainly available as an aqueous solution, and in these solutions the aldehydegroups are hydrated.
Glutaraldehyde usage Royalpharm
A glutaraldehyde solution of 0.1% to 1.0% concentration may be used for system disinfection and as a preservative for long term storage. It is a sterilant, killing endospores in addition to many microorganisms and viruses.
Glutaraldehyde is used in biochemistry applications as an amine-reactive homobifunctional crosslinker and fixative prior to SDS-PAGE, staining, or electron microscopy. It kills cells quickly by crosslinking their proteins and is usually employed alone or mixed with formaldehydeas the first of two fixative processes to stabilize specimens such as bacteria, plant material, and human cells. A second fixative procedure uses osmium tetroxide to crosslink and stabilize cell and organellemembrane lipids. Fixation is usually followed by dehydration of the tissue in ethanol or acetone, followed by embedding in an epoxy resin or acrylic resin.
Another application for treatment of proteins with glutaraldehyde is the inactivation of bacterial toxins to createtoxoid vaccines,
A solution of glutaraldehyde, typically of 10% w/w, is sold under various trade names to remove common and plantar warts. It is said to inactivate viruses and bacteria, and to dry the skin, facilitating physical removal of the wart. Trade names include Diswart Solution and Glutarol.
Hydraulic fracturing (fracking) fluid
Glutaraldehyde is a component of hydraulic fracturing "fracking" fluid. It is included in the additive called Alpha 1427, as a biocide. Bacterial growth can impair the production of oil and gas wells, and can be introduced into the formation from various sources including the source water, proppant, and polymer used in the hydraulic fracturing process. Glutaraldehyde is pumped as a liquid additive with the fracturing fluid to reduce or eliminate this source of formation and fracture conductivity damage.
Aquariums with plants
Glutaraldehyde is an ingredient in a product for freshwater aquariums as a source of bioavailable organic carbon used by aquatic plants.