Pharmaceutical Intermediates, Syntheses Material Intermediates
USP EP JP etc.
Aluminum foil bag
Cool and dry
1000 Kilogram/Kilograms per Month
Packaging & Delivery
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
ShangHai GuangZhou QingDao etc.
Prompt delivery after payment confirmed by air courier or by sea
XABC Biotech ,.Ltd
An organic compound whose main purpose is to make epoxy resin. It is also an oxygen-containing substance stabilizer and chemical intermediate. The main raw materials of epoxy and phenoxy resin; glycerin; maturation of propylene-based rubber; fiber Solvents for esters and ethers; high wet strength resins for the paper industry. Poisonous, moderately toxic, animal experiments prove potentially carcinogenic, long-term exposure should be avoided1. Avoid contact with acids, bases, ammonia, amines, copper, magnesium aluminum and their alloys. Miscible with most organic solvents, slightly soluble in water. It also has strong solvency for varnish, natural and synthetic resins. Flammable, vapor and air can form an explosive mixture, explosive limit 5.23% -17.86% (volume fraction). Chemically active, can produce esters: reaction with alcohols and phenol can generate ether; with aldehydes or ketones to dioxane derivatives. When reacting with this product, it is advisable to dilute it with an inert solvent and add it slowly for safety reasons. This product is toxic, pay attention to air circulation, operators should wear protective equipment. Sand, foam, dry powder, carbon dioxide can be used on fire. 2. Chemical Properties: 3-Chloro-1,2-epoxypropane reacts with water to produce 3-chloropropanediol. It reacts with hydrochloric acid to produce β,β'-dichloroisopropanol. An addition reaction with hydrogen cyanide generates γ-chloro-β-hydroxybutyronitrile. Reducing allyl alcohol with sodium or sodium amalgam. Reaction with hydrogen sulfide to produce 1-chloro-3-mercapto-2-propanol and the like. Reacts with alcohols and phenols in the presence of a catalyst to produce α-chloroethanol-γ-ether, glycidyl ether or glycerol-α,γ-diether. 3.3-Chloro-1,2-epoxypropane reacts with ammonia or amines to produce 1,3-diaminopropanol and N-substituted products. Reaction with aldehydes or ketones gives dioxane derivatives. Reacts with sodium salts of β-keto acid esters and malonic acid esters to obtain γ-lactone derivatives. 3-Chloro-1,2-epoxypropane can be polymerized using hydrogen fluoride or boron fluoride as a catalyst. 4. Poisonous, can be absorbed by the skin and stimulate the skin and mucous membranes. At higher concentrations, there is anesthetic effect. When there is poisoning, there are tingling eyes, conjunctivitis, rhinitis, tears, cough, tiredness, gastrointestinal disorders, nausea and other symptoms. Severe poisoning can cause anesthesia and even cause lung, liver and kidney damage. The human body inhales MLC20*10-6. Rat oral LD5090mg/kg. The maximum allowable concentration in air is 18mg/m3. Production equipment must be closed and air must be circulated. Operators must wear protective equipment. In addition, epichlorohydrin has a tendency of intense self-aggregation and should not be heated in an open flame to prevent the container from bursting. When used as a reagent for reaction, it should be diluted with an inert solvent and slowly added.