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Melatonine 99% Melatonin cas#73-31-4 Increase sleep

  • 1-9 Kilograms
    $177.00
  • >=10 Kilograms
    $170.00
Quantity:
- + Kilograms available
0piecesselected, US $in total
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Shipping fee:
Depends on the order quantity.
Lead Time:
5 day(s) after payment received
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Overview
Quick Details
Type:
Semisynthesis
Form:
Powder
Part:
synthesis
Extraction Type:
Liquid-Solid Extraction
Packaging:
bottle, DRUM, Vacuum Packed
Place of Origin:
Shaanxi, China
Grade:
raw material
Brand Name:
LISI
Model Number:
/
Product Name:
Melatonine
Appearance:
White Powder
Specification:
99%
Test Method:
HPLC
Molecular Formula:
C13H16N2O2
CAS#:
73-31-4
MOQ:
1Kg/bag
Product uses:
Melatonin receptors activate melatonin
Other use:
Sleep
Shelf Life:
2 Years

Packaging & Delivery

Selling Units:
Single item
Single package size: 
10X20X5 cm
Single gross weight:
1.500 kg
Package Type:
Can be packed according to customer's requirements
Lead Time :
Quantity(Kilograms) 1 - 1 2 - 25 >25
Est. Time(days) 5 7 To be negotiated
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Product Description

Melatonine 99% Melatonin cas#73-31-4 Increase sleep 1Kg/bag

Product Name Melatonine Specification 98%
Other names Melatonin Appearance White Fine Powder
CAS No. 73-31-4 Molecular Formula C8H14BrNO2
Test Method HPLC Molecular Weight 236.11
MOQ 1kg/bag Place of Origin Xi'an, China (Mainland)
Shelf Time 2 Years Storage Keep Dry and Keep away from Sunlight


Melatonin is a hormone made from the pineal gland that activates the melatonin receptor. Melatonin plays a role in sleep and has important antioxidant and anti-inflammatory properties.

 

In vivo studies

Melatonin increased the levels of activated PTEN, rsk-1, mTOR and AMPK α kinases, mildly inhibited erk-1 / 2 phosphorylation and dephosphorylation, significantly inhibited the phosphorylation of S6 ribosomal protein, 4E-BP1, GSK-3 α and GSK-3 β, and slightly increased the phosphorylation of pras40 in animals [1]. Melatonin improves neurotoxicity and astrocyte activation induced by a β 1-42 in cerebral cortex. Melatonin also blocked a β 1-42 induced reduction in the expression of Reelin and Dab1 [2]. Melatonin treatment and NLRP3 - / - deficiency have similar inhibitory effects on NF - κ B and NLRP3 signaling pathways in mice. Melatonin treatment and NLRP3 - / - deficiency share some clock gene expression patterns and improve cardiomyocyte morphology in mice [3].

 

Preparation of melatonin

1. Melatonin exists in the pineal gland of mammalian brain. Generally, bovine pineal gland is freeze-dried and grinded into powder. The fat is removed by petroleum ether and mixed with deionized water to form a slurry. After centrifugation, the supernatant is taken and extracted with equal volume of ethyl acetate. After vacuum drying, the crude product of melatonin is obtained and recrystallized Get the best.

 

 

Product display

Company Information

History: LISIHERB ,which engaged in the natural ingredients' research & development (R & D), production and selling. Providing the high-quality natural materials for manufacturers and enterprises of botanical drug, health food, beverage, cosmetic etc.
    Certification: Our company is certified with quality management system such as HACCP/ISO/Kosher certification, and equiped with UV/HPLC/GC/AA and other morden analyzing instruments to assure high quality.
    Factory: LISI's factory covers an area of 35000 square metre, and the production workshop is designed according to GMP stantard. It is a standardized, large size phytochemistry factory which equiped with complete equipments of extraction, (12 multi-function extraction tanks ect.), separation, concentration, dehydration, sterilization etc. 

Packaging & Shipping

 

FAQ

Q1.How to place an order?

A: Choose products you need→Send inquire to us→Communicate→Confirm prices and details→Getting the freight and balance →Ship the goods→After sales service.  

Q2.What is your delivery term and delivery period? 

A: We often ship product by exress. But you can choose the one which is the most convenient or cost effective for you. Delivery time is about 3--5days.I

Q3. What is your package?
A: Powder: PE bag, glass bottle,bubble film or PTFE bottle for inner packing, and aluminium foil bag for outer packing.
   

About Us

1. 100%natural source

2. Stable availability, adequate stock, complete specification and reasonable price

3. MOQ : 100mg

4. ISO certification

5. The strong support of advanced technology and detection capability 

Contact Us: 17719587196(Wechat)