Coenzyme Q10 is the 3rd most sold dietary ingredient in the United States after omega-3 and multivitamins. 1.Mitochondrial disorders Supplementation of coenzyme Q10 is a treatment for some of the very rare and serious mitochondrial disorders and other metabolic disorders, where patients are not capable of producing enough coenzyme Q10 because of their disorder Coenzyme Q10 is then prescribed by a physician. 2.Heart health Coenzyme Q10 helps to maintain a healthy cardiovascular system. There is evidence of CoQ10 deficiency in heart failure . 3.Migraine headaches Supplementation of coenzyme Q10 has been found to have a beneficial effect on the condition of some sufferers of migraine headaches. 4.Blood pressure There are several reports concerning the effect of CoQ10 on blood pressure in human studies. 5.Periodontal disease Human clinical trials have suggested a link between oral administration of CoQ10 and improved gingival health, immune response in gum tissues, and a reversal of the diseased gum conditions. 6.Lifespan One study demonstrated that low dosages of coenzyme Q10 reduce oxidation and DNA double-strand breaks, and a combination of a diet rich in polyunsaturated fatty acids and coenzyme Q10 supplementation leads to a longer lifespan in rats.