The usage: 1. To choose the proper sizes pouches as per the size the equipment's to be sterilized. and the put the clean and dry equipment into the pouches. The equipment should be less than 3/4 of the sizes of the pouches to ensure the seal successfully and avoid the break of the pouches. 2. Make the acuate edge of the equipment to be contrary to the peeling direction, during putting the acuate equipment in to the pouches. 3. Tear the stick indicating paper and put it into the pouches. stick and close the pouches, marking the detailed informations, such as the sterilization date, the equipment name and the usage etc. 4. put the closed pouches into the steam clave or ETO sterilizer, according to the rule to let the pouches' paper side against paper side, and then do the sterilization as per the normal methods. 5. To identify the situation of indicator's color change: if sterilization proceeded, it will turn black from initial blue based on steam sterilization method, and will turn brown from initial pink based on the ETO sterilization method. 6. Store the sterilized pouches dry, clean and dark-light place. 7. tear the pouches as per the peeling direction and put the sterilized equipment out. The notes: 1. The valid period will be 6 months on the steam sterilization method basis and will be 24 months on the ETO sterilization methods basis. 2. Do not use if pack is damaged.