Particle Size | High-resolution separation, method development | Industry: 5µm (ISO 3107) ▲ IKEME Base: 5µm (matches standard) ▲ IKEME Advanced: 3µm (ISO 3107) (smaller particles enable higher resolution) | Base maintains compatibility; Advanced improves resolution for complex samples | Advanced requires higher-pressure systems (e.g., UHPLC) |
Column Dimensions | Routine analysis, long retention times | Industry: 150x4.6mm (ASTM) ▲ Base: 150x4.6mm ▲ Advanced: 250x4.6mm (ISO 10726) (longer column for extended retention) | Base standard for most methods; Advanced offers flexibility for specific needs | Longer columns may increase analysis time or cost |
Surface Chemistry | Non-polar compound analysis | Industry: Standard C18 (ASTM) ▲ Base: C18 with standard bonding ▲ Advanced: End-capped C18 (USP <621>) (reduces peak tailing) | Advanced minimizes peak tailing for better accuracy in critical analyses | Base may show tailing in polar or acidic conditions |
pH Stability Range | Acidic/basic sample analysis | Industry: pH 2–8 ▲ Base: pH 2–10 ▲ Advanced: pH 1–14 (ISO 10993) (handles extreme pH conditions) | Advanced enables analysis of highly acidic/basic samples (e.g., drug formulations) | Base may degrade at extreme pH levels |
Temperature Stability | High-temperature methods | Industry: Up to 60°C ▲ Base: 60°C ▲ Advanced: 80°C (ASTM D3987) (operates at elevated temperatures) | Advanced supports methods requiring thermal stability (e.g., protein denaturation) | Base limited to standard temperatures |
Packaging Compliance | EU market access, regulatory compliance | Industry: Varies by region ▲ Base: EPR Germany Packing (complies with German packaging laws) ▲ Advanced: EPR France + Germany (dual EU compliance) | Advanced ensures seamless export to multiple EU markets | Base may restrict access to regions requiring additional certifications |