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Health empty capsule shells are widely used in medicine, specifically for packing powders, granules, and sometimes even liquids. There are many kinds of empty capsule shells that can help to deliver curative substances. Following are the various types of health-empty capsule shells:
Gelatin capsules
Gelatin capsules are created using animal-derived gelatin. They are the most widely used type of capsule due to their affordability and versatility. Gelatin capsules dissolve quickly in the stomach, making them ideal for substances that require immediate absorption. This type of health-empty capsule shell is often used in pharmaceuticals and dietary supplements.
Vegetarian capsules
Vegetarian capsules, often made from plant-derived cellulose materials like hydroxypropyl methylcellulose (HPMC) or pullulan, provide a suitable alternative to gelatin capsules for vegan and vegetarian consumers. They have similar dissolving properties but usually cost a little more than their competitors. They are increasingly becoming popular in the supplement market due to the growing demand for vegan and vegetarian-friendly products.
Enteric-coated capsules
Enteric-coated capsules are coated with a special material that prevents the capsule from dissolving in the stomach. Instead, the capsule is designed to dissolve in the more alkaline environment of the intestines. This type of capsule is useful for protecting sensitive ingredients from stomach acid, ensuring targeted release. Also, this type of health-empty capsule shell is used for substances that may cause irritation to the stomach lining, such as fish oil or certain medications.
Sustained-release capsules
Sustained – sustained release capsules are designed to release their contents gradually over an extended period. This is beneficial for increasing medication adherence and maintaining stable levels of active ingredients in the bloodstream. These are useful for maximizing effectiveness and minimizing side effects. Sustained release is particularly beneficial for those patients who cannot take their medication frequently.
Capsule-in-capsule systems
These innovative designs allow for multiple ingredients to be encapsulated separately within a single capsule. It is ideal for complex formulations that require the combination of two or more substances. These are still relatively new in the market compared to more established capsule types but offer an innovative solution for increasingly complex supplement and medication needs.
Gelatin
As stated earlier, gelatin is derived from collagen in animal tissues, bones, and skin. It has been used to manufacture the most common type of capsule because of its gelling properties. It is flexible, easy to process, and relatively inexpensive. This allows them to easily be incorporated into pharmaceutical and supplement products. Gelatin capsules have a quick dissolution time, usually between 10 and 15 minutes in the digestive system. This is ideal for substances that require immediate absorption, such as vitamins, pain relievers, and antibiotics.
Vegetable cellulose
Also called hydroxypropyl methylcellulose (HPMC), cellulose capsules are manufactured using plant-derived cellulose polymers. The primary material used is pulled apart from the cellulose that is extracted from plants. This type of capsule offers a vegan and vegetarian alternative to conventional gelatin capsules. Unlike gelatin capsules, cellulose capsules have a dissolution time of around 30 minutes. This is suitable for a broader range of products, including those targeting vegan or kosher markets.
Fish gelatin
Fish gelatin is derived from the collagen of fish skins and bones. It is often used to create capsules for consumers who are neither vegetarian nor vegan but do not consume beef or pork products. The dissolution time of fish gelatin capsules is comparable to that of bovine gelatin, usually within 10 to 15 minutes.
Agari
Agari is a natural gelling agent that is derived from red seaweeds or agarose. It is rich in agarose and agaropectin, which are ideal for making empty capsules. It is a suitable option for vegetarian or vegan-friendly products. Agar capsules, although less common, offer a plant-based alternative to gelatin with similar encapsulation properties.
Pullulan
Pullulan is a gum made from the fermentation of starch by the fungus Aureobasidium pullulans. It is used to make capsules known for their superior oxygen barrier properties and natural origin. This makes it ideal for keeping sensitive substances away from light, air, and moisture. Pullulan capsules are not as widely used as gelatin or HPMC capsules but are increasingly gaining popularity due to their biodegradability and suitability for clean label products.
The key specifications for health-empty capsule shells include:
Tamper Evident:
Further enhancing their attractiveness, capsule shells are designed to be tamper-evident. This ensures safety to the consumers and alerts them in case the product has been compromised.
Health empty capsule shells play a key role in the following scenarios:
Pharmaceutical Applications
In the pharma world, capsule shells are mainly used to contain drugs in powder or pellet form. They make it easy to deliver drugs and can replace hard tablets in many cases. The quick dissolving gelatin capsules are especially useful for drugs that need quick absorption. They ensure that active ingredients are efficiently delivered to the target site in the body. In recent years, enteric capsules have also been developed for drugs that need to be released in the intestines rather than the stomach, such as acid-sensitive antibiotics, anti-ulcer drugs, and other targeted therapies.
Dietary Supplements
Health-empty capsule shells are frequently utilized to package vitamins, minerals, and herbal supplements. Apart from being vegetarian-friendly, capsule manufacturers have found that cellulose capsules generally have a longer shelf life than gelatin capsules. This makes them suitable for products that require extended storage conditions. This is especially when planning mass distribution. The pullulan capsule is also a great option because it is manufactured with superior oxygen barrier properties.
Custom formulations for Specific Needs
Capsule shells can be tailored to infants and patients who have difficulty swallowing standard-sized capsules. For example, these smaller-sized capsules are intended primarily for pediatric use. They allow easy and safe medication administration to children who cannot take larger pills or tablets. As for geriatric patients, there are specially designed capsule shells with a smoother surface. This makes it easier for them to swallow since they tend to have more difficulties than the average adult. There are also flavor-masking capsules that conceal the unpleasant tastes of certain medications. This improves overall medication adherence and effectiveness.
Cosmetic and Beauty Products
Health-empty capsule shells are also used in the beauty segment to deliver active ingredients such as collagen, hyaluronic acid, and vitamins. These are encapsulated within a capsule for skincare supplements that promise enhanced absorption and effectiveness in such products. The encapsulation technology being employed here ensures that these delicate ingredients remain stable and potent until they are ready to be applied.
Purpose
Capsules have many uses, ranging from medication to dietary supplements. Understanding the usage will help the users select the most suitable type. For example, gelatin capsules are more suitable for users who want capsules with fast dissolution. On the other hand, if the customers want a capsule suitable for a vegan product, they must go for HPMC capsules.
Ingredients
The type of formulation that will be stored inside the capsule should also be considered. For example, at rainbowcms, we always advise clients to get enteric-coated capsules for acid-sensitive substances like fish oil and vitamin c. Suppliers should also ensure that potential customers get capsules that suit the ingredients they want to encapsulate. For example, titanium oxide is added to the shell to protect light-sensitive materials.
Product
Customer preferences also play a major role in influencing the decision of which capsule to go for. Once customers know the benefits and materials of each capsule, they will make a decision that will suit their dietary needs. Manufacturers and wholesalers should keep in mind that how the capsule looks will also affect the poem's market potential. In this case, offer the customers a variety of colors and sizes that will match their medication.
Supplier reputation
To ensure that the capsules are of high quality and manufactured under hygienic conditions, customers should get health-empty capsules from reputable suppliers. For example, we at rainbowcms work hard to ensure healthy and excellent empty capsule shells for every Iranian and customer who wishes to buy in bulk.
Materials
This article has shown that different capsule shells are made of different materials suitable for distinct dietary needs. For vegans and vegetarians, the capsule is usually made from cellulose. For customers who experience difficulty in swallowing, we at rainbowcms recommend enteric capsules which are smaller in size. Concerning color, we have picked the most popular colors for the shells, such as green, blue, red, and black.
A1. Keep them in a tight, dry spot away from direct sunlight and strong heat. Don't put them near kitchens or bathrooms where heat and moisture are common. Avoid refrigerators since they can cause condensation.
A2. Vegetarian capsules are healthier than gelatin capsules since they are crafted from plant-derived materials. They are suitable for individuals who adhere to a vegan or vegetarian diet, as well as those who are religious and prefer Kosher or Halal alternatives.
A3. When stored correctly, empty capsules can last up to 2-3 years. Nevertheless, the expiration date can differ based on the specific sort of capsule and environmental conditions. Always check the package for an expiration date.
A4. If the shell appears discolored, breaks easily when handled, or if it starts sticking or clumping together, it has probably gone bad. A strange odor or a change in texture can also mean that the shell has really gone bad.
A5. Consuming an expired capsule shell may not be dangerous, but it is not recommended. The potency of the encapsulated substance may be reduced. In some cases, the capsule may not dissolve properly in the stomach.